We present a total synthesis of hyalodendriol C, a fungal natural product. We have focused on the use of palladium-catalyzed intramolecular biaryl coupling reaction of phenyl benzoate derivatives to synthesize hyalodendriol C. Keeping in view, the indispensable biological values of this compound, we took the advantage of our established strategy to chemically synthesize hyalodendriol C. The total synthesis of hyalodendriol C got accomplished in 10 steps beginning with the preparation of phenol derivative from the commercially available 5-methylbenzene-1,3-diol and synthesis of the corresponding benzoic acid derivative.

中文翻译：

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Hyalodendriol C的全合成

我们展示了一种真菌天然产物 hyalodendriol C 的全合成。我们专注于使用钯催化的苯甲酸苯酯衍生物的分子内联芳偶联反应来合成 hyalodendriol C。考虑到该化合物不可或缺的生物学价值，我们利用我们既定的策略化学合成 hyalodendriol C。 hyalodendriol C的全合成从市售的5-甲基苯-1,3-二醇制备苯酚衍生物和合成相应的苯甲酸衍生物开始，分10步完成。