Objective To evaluate the effect of weightlifting (leg press) on intraocular pressure (IOP). Design Prospective cohort study. Subjects A total of 24 participants met the inclusion criteria and completed the study procedures. Participants had an average age of 22.7±2.7 years and included nine women. The mean baseline IOP was 13.9 mm Hg (SD=2.4) with an average body mass index of 24.5 (SD= 3.1). Methods The maximum load for a single lift was found for each participant. Participants then performed three leg press regimens: one repetition using 95% of maximal load (1RM), six repetitions using 75% of maximal load (6RM) and isometric push against a weight much heavier than maximal load (ISO). Main outcome measure IOP was measured pre-exercise, during and immediately following the exercise using an iCare TA01i rebound tonometer. Blood pressure and HR were being monitored continuously during the lift. Optical coherence tomography images were obtained pre and postexercise session. Results The average maximum weight lifted by our participants was 331.9 Kg (SD=97.3). Transient increased IOP was observed across the 1RM, 6RM and ISO exercises with an average increase in 26.4 mm Hg (23.7 mm Hg to 28.7 mm Hg) to reach an average max IOP of 40.7 mm Hg (27.8 mm Hg to 54.2 mm Hg), with an absolute maximum of 70 mm Hg in one participant. Conclusions There is a transient and dramatic fluctuation in IOP with resistance training. This coupled with regular exposure to resistance training is potentially a significant risk factor for glaucoma. It should be noted that this study has been carried out in a healthy young population, and, thus, the external validity of these results in glaucoma participants requires further investigation. Data are available upon request.

中文翻译：

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抗阻运动时眼压波动

目的评价举重（压腿）对眼压（IOP）的影响。设计前瞻性队列研究。受试者 共有 24 名参与者符合纳入标准并完成了研究程序。参与者的平均年龄为 22.7±2.7 岁，其中包括 9 名女性。平均基线 IOP 为 13.9 mm Hg (SD=2.4)，平均体重指数为 24.5 (SD=3.1)。方法 为每个参与者找到单次电梯的最大负载。然后参与者进行了三种腿部推举方案：使用 95% 的最大负荷 (1RM) 重复一次，使用最大负荷的 75% (6RM) 重复六次，以及对比最大负荷重得多的重量 (ISO) 进行等长推。主要结果测量 IOP 是在运动前、运动期间和运动后立即使用 iCare TA01i 反弹眼压计测量的。在举升过程中持续监测血压和心率。在运动前和运动后获得光学相干断层扫描图像。结果 我们的参与者平均举起的最大重量为 331.9 Kg (SD=97.3)。在 1RM、6RM 和 ISO 练习中观察到瞬时增加的眼压，平均增加 26.4 毫米汞柱（23.7 毫米汞柱至 28.7 毫米汞柱），达到 40.7 毫米汞柱（27.8 毫米汞柱至 54.2 毫米汞柱）的平均最大眼压，一名参与者的绝对最大值为 70 毫米汞柱。结论 阻力训练后眼压会出现短暂且剧烈的波动。再加上经常接受阻力训练，这可能是青光眼的一个重要风险因素。应该指出的是，这项研究是在健康的年轻人群中进行的，因此，这些结果在青光眼参与者中的外部有效性需要进一步调查。数据可应要求提供。