In the current research, magnesium and its alloys have been intensively studied as resorbable implant materials. Magnesium materials combine their good mechanical properties with bioactivity, which make them interesting for guided bone regeneration and for the application as barrier membranes. In this study, the in vitro degradation behavior of thin magnesium films was investigated in cell medium and simulated body fluid. Three methods were applied to evaluate corrosion rates: measurements of (i) the gaseous volume evolved during immersion, (ii) volume change after immersion, and (iii) polarization curves. In this comparison, measurements of H₂ development in Dulbecco's modified Eagle's medium showed to be the most appropriate method, exhibiting a corrosion rate of 0.5 mm·year⁻¹. Observed oxide and carbon contamination have a high impact on controlled degradation, suggesting that surface treatment of thin foils is necessary. The bioactivity test showed positive results; more detailed tests in this area are of interest.

中文翻译：

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镁屏障膜的生物活性和腐蚀行为

在目前的研究中，镁及其合金作为可吸收植入材料得到了深入研究。镁材料将其良好的机械性能与生物活性相结合，这使它们对引导骨再生和作为屏障膜的应用很感兴趣。在这项研究中，研究了镁薄膜在细胞培养基和模拟体液中的体外降解行为。应用三种方法来评估腐蚀速率：测量 (i) 浸入过程中产生的气体体积，(ii) 浸入后的体积变化，以及 (iii) 极化曲线。在该比较中，Dulbecco 改良 Eagle 介质中 H ₂发展的测量表明是最合适的方法，腐蚀率为 0.5 mm·年^-1. 观察到的氧化物和碳污染对受控降解有很大影响，这表明薄箔的表面处理是必要的。生物活性测试显示阳性结果；这方面更详细的测试很有趣。