Vermamoeba vermiformis are one of the most prevalent free-living amoebae. These amoebae are ubiquitous and also thermotolerant. Of concern, V. vermiformis have been found in hospital water networks. Furthermore, associations between V. vermiformis and pathogenic bacteria have been reported, such as Legionella pneumophila. Moreover, V. vermiformis are well known to host viruses, bacteria, and other microorganisms and cases of keratitis due to V. vermiformis in conjunction with other amoebae have been reported. Despite the preceding, the medical importance of V. vermiformis is still an ongoing discussion and its genome has been only recently sequenced. Herein, we present a review of the current understanding of the biology and pathogenesis pertaining to V. vermiformis, as well as its’ role as an etiological agent and trojan horse. An approach known as theranostics which combines both diagnosis and therapy could be utilized to eradicate and diagnose keratitis cases caused by such amoebae. Given the rise in global warming, it is imperative to investigate these rarely studied amoebae and to understand their importance in human health.

中文翻译：

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Vermamoeba vermiformis 的重要性日益增加

Vermamoeba vermiformis是最普遍的自由生活变形虫之一。这些变形虫无处不在，而且耐热。值得关注的是，V。 在医院供水网络中发现了蠕虫。此外，V之间的关联。 已报道蠕虫和致病菌，如嗜 肺军团菌。此外，V。 vermiformis是公知的宿主的病毒，细菌和其他微生物和角膜炎例因V。 据报道，蠕虫与其他变形虫一起发生。尽管有上述作用，但在医学上的重要性伏。 vermiformis仍在讨论中，其基因组最近才被测序。在此，我们回顾了目前对V的生物学和发病机制的理解。 vermiformis，以及它作为病原体和特洛伊木马的作用。一种称为治疗诊断学的方法结合了诊断和治疗，可用于根除和诊断由此类变形虫引起的角膜炎病例。鉴于全球变暖的加剧，有必要调查这些很少被研究的变形虫并了解它们对人类健康的重要性。