Introduction: Differences in cognitive performance with exercise between men and women have previously been reported. In this study, we evaluated between-sex differences in oxygenation of the prefrontal cortex (PFC) with moderate-intensity aerobic exercise (AE), which could contribute to noted differences in cognitive function. Method: The subjects were ten men (age, 21.5 ± 0.5 years; height, 171.7 ± 4.8 cm; weight, 65.6 ± 5.6 kg) and ten women (age, 21.4 ± 0.5 years; height, 157.6 ± 4.9 cm; weight, 51.3 ± 6.5 kg). They completed our AE protocol, consisting of a 30-min leg-ergometer cycling at an intensity of 50% peak oxygen uptake, with an initial 4-min rest period for baseline measurement. Measures of the dynamics of cerebral oxygenation included: oxygenated hemoglobin (O2Hb) in the left and right PFC (LR-PFC) and deoxygenated hemoglobin (HHb). The 30-min exercise period was subdivided into six 5-min phases, with the average and peak values determined in each phase. Results: A significant interaction was found between LR-PFC HHb and sex (p < 0.001), with significantly higher values in men than in women in phases 3–6 (p < 0.05). Conclusion: We report a significant sex effect of HHb in the LR-PFC.

中文翻译：

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中等强度运动时左右前额叶皮层充氧的性别差异

简介：先前已经报道了男女在运动方面的认知表现差异。在这项研究中，我们评估了中度有氧运动（AE）对前额叶皮层（PFC）的充氧之间的性别差异，这可能会导致认知功能的明显差异。方法：受试者为十名男性（年龄21.5±0.5岁;身高171.7±4.8厘米;体重65.6±5.6公斤）和十名女性（年龄21.4±0.5岁;身高157.6±4.9厘米;体重51.3 ±6.5公斤）。他们完成了我们的AE方案，包括以30％的腿部测力计在50％的峰值吸氧强度下循环，并在初始的4分钟休息时间内进行基线测量。脑氧合动力学的指标包括：左右PFC（LR-PFC）中的氧合血红蛋白（O2Hb）和脱氧血红蛋白（HHb）。30分钟的运动时间分为六个5分钟的阶段，每个阶段确定平均值和峰值。结果：发现LR-PFC HHb与性别之间存在显着的相互作用（p <0.001），在3-6期中，男性的价值明显高于女性（p <0.05）。结论：我们报道了在LR-PFC中HHb的显着性效应。