Mythical figures have been part of human cultural tradition for centuries, worldwide. Some of them were totally imaginary, others were likely inspired by individuals with malformation syndromes, while others are composites of parts of different species. Various artists have created works of art based on these mythical or hybrid beings, such as cyclops and chimeras. The plethora of representations of artworks in ancient, but also contemporary art (statues, paintings, illustrations, photographs, installations) is proof that they still continue to be a source of inspiration, although their rendering and interpretation have changed over time. Contemporary medical genetic knowledge has revealed the underlying pathogenesis and causative molecular basis of malformation syndromes and delineates the corresponding phenotypes. Today, many figures once viewed as mythical are reflected in living humans with medical diagnoses. Ancient terms that arose in mythology—cyclopia, chimera/ism, and others—live on in the medical literature.

中文翻译：

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艺术和遗传学中的神话人物：对独眼和嵌合的当前观点

几个世纪以来，神话人物一直是世界范围内人类文化传统的一部分。其中一些完全是虚构的，另一些很可能受到患有畸形综合症的个体的启发，而另一些则是不同物种部分的复合物。各种艺术家根据这些神话或混合生物创作了艺术作品，例如独眼巨人和嵌合体。古代艺术作品和当代艺术作品（雕像、绘画、插图、照片、装置）的大量表现证明它们仍然是灵感的源泉，尽管它们的渲染和解释随着时间的推移而发生了变化。当代医学遗传知识揭示了畸形综合征的潜在发病机制和致病分子基础，并描绘了相应的表型。今天，许多曾经被视为神话的人物都反映在有医学诊断的活人身上。神话中出现的古代术语——独眼、嵌合/主义等——在医学文献中仍然存在。