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Imaging of vascular abnormalities in ocular surface disease
Survey of Ophthalmology ( IF 5.1 ) Pub Date : 2021-05-13 , DOI: 10.1016/j.survophthal.2021.05.001
Vito Romano 1 , Bernhard Steger 2 , Mohammad Ahmad 3 , Giulia Coco 4 , Luca Pagano 5 , Sajjad Ahmad 6 , Yitian Zhao 7 , Yalin Zheng 8 , Stephen B Kaye 1
Affiliation  

The vascular system of the ocular surface plays a central role in infectious, autoimmune, inflammatory, traumatic and neoplastic diseases. The development, application, and monitoring of treatments for vascular abnormalities depends on the in vivo analysis of the ocular surface vasculature. Until recently, ocular surface vascular imaging was confined to biomicroscopic and color photographic assessment, both limited by poor reproducibility and the inability to image lymphatic vasculature in vivo. The evolvement and clinical implementation of innovative imaging modalities including confocal microscopy, intravenous, and optical coherence tomography–based angiography now allows standardized quantitative and functional vascular assessment with potential applicability to automated analysis algorithms and diagnostics.



中文翻译:

眼表疾病血管异常的成像

眼表的血管系统在感染、自身免疫、炎症、创伤和肿瘤疾病中起着核心作用。血管异常治疗的开发、应用和监测取决于眼表脉管系统的体内分析。直到最近,眼表血管成像仅限于生物显微镜和彩色摄影评估,两者都受到重复性差和无法在体内成像淋巴脉管系统的限制. 包括共聚焦显微镜、静脉内和基于光学相干断层扫描的血管造影在内的创新成像模式的发展和临床实施现在允许标准化的定量和功能性血管评估,并可能适用于自动分析算法和诊断。

更新日期:2021-05-13
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