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Tangutidines A–C, Three Amphoteric Diterpene Alkaloids from Aconitum tanguticum
Natural Products and Bioprospecting Pub Date : 2021-05-12 , DOI: 10.1007/s13659-021-00310-3
Hao-Yi Li 1, 2 , Bing-Chao Yan 1 , Li-Xin Wei 3 , Han-Dong Sun 1 , Pema-Tenzin Puno 1
Affiliation  

Three new diterpene alkaloids, tangutidines A–C (13), and four known alkaloids (47) were isolated from the whole plant of Aconitum tanguticum, from which amphoteric diterpene alkaloids (13) were obtained for the first time. The structures of 13 were elucidated by detailed interpretation of spectroscopic data, including MS and NMR data. All of them were evaluated for their cytotoxic activities.

Graphic Abstract



中文翻译:

tangutidines A–C,三种来自唐古乌头的两性二萜生物碱

三个新的二萜生物碱,tangutidines A-C(1 - 3),和四个已知生物碱(4 - 7)从全植物分离乌头大黄,从该两性二萜生物碱(1 - 3分别是第一次获得) 。的结构1 - 3通过光谱数据,包括MS和NMR数据的详细解释说明。对它们全部进行细胞毒性活性评估。

图形摘要

更新日期:2021-05-12
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