The adoption of flow technology for the manufacture of chemical entities, and in particular pharmaceuticals, has seen rapid growth over the past two decades with the technology now blurring the lines between chemistry and chemical engineering. Current indications point to a future in which flow chemistry and related technologies will be a major player in modern chemical manufacturing and the 4th industrial revolution. In this review we highlight the application of new reactor configurations and designs in the context of either bespoke or commercial flow apparatus specifically related to microwave chemistry, photochemical transformations, electrochemical promoted reactions and multi-phasic reactions. In addition, we look at how 3D printing in reactor design and computer-aided automation is growing within the field and finally describe how innovative solutions are being developed to tackle challenging down-stream processing operations.

中文翻译：

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反应器工程概念在连续流化学中的应用：综述

在过去的二十年中，流技术在化学实体特别是制药领域的采用迅速增长，该技术现在模糊了化学与化学工程之间的界线。当前的迹象表明，未来流化学和相关技术将成为现代化学制造和第四次工业革命的主要参与者。在这篇综述中，我们着重介绍了新的反应器配置和设计在定制或商用流动设备中的应用，这些设备与微波化学，光化学转化，电化学促进的反应和多相反应特别相关。此外，