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Ribosomal protein genes as sensors of aneuploidy
Nature Reviews Genetics ( IF 42.7 ) Pub Date : 2021-05-07 , DOI: 10.1038/s41576-021-00373-5
Caroline Barranco 1
Affiliation  

During development, cell competition causes apoptosis of cells with abnormal ribosomal protein profiles. Ji et al. show that this same mechanism also deletes aneuploid cells and that the deleted cell populations mainly have altered ribosomal protein gene dosages.

中文翻译:

核糖体蛋白基因作为非整倍体的传感器

在发育过程中,细胞竞争导致具有异常核糖体蛋白谱的细胞凋亡。姬等人。表明这种相同的机制也会删除非整倍体细胞,并且删除的细胞群主要改变了核糖体蛋白基因剂量。
更新日期:2021-05-08
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