Winter rainfall over southern China is usually enhanced when Madden-Julian oscillation (MJO) is active over the Indian Ocean, but it can be weakened under certain conditions. Here, the diversity of MJO impacts on winter rainfall and its mechanisms are explored by using scenarios of enhanced and suppressed rainfall anomalies over southern China when MJO is active over the Indian Ocean. The combined effects of low-frequency background moisture and intraseasonal winds are the major contributors to the different rainfall anomalies. Anomalous circulation in mid-high latitudes, especially on intraseasonal timescales, is almost opposite in the two scenarios, which can modulate the response of extratropical atmosphere to MJO heating and then induces the different circulations over southern China. In the enhanced scenario, mid-high latitudes of Eurasia and southern China are dominated by positive and negative sea level pressure anomalies, respectively. The southerly over southern China and the South China Sea induced by MJO heating promotes the anomalous moisture convergence and ascending motion over southern China, resulting in the enhanced rainfall. In the suppressed scenario, however, the circulation in mid-high latitudes does not favor rainfall over southern China and leads to the northerly response to MJO heating over southern China, which enhances moisture divergence and weakens rainfall over southern China.