Polyamine plays the important role in human body. Here, the convenient synthesis of AIE material 2-(pyren-1-ylmethylene) malononitrile (L) was capable of fluorescent recognition for 1, 3-diaminopropane in gas-liquid-solid three-phase with good selectivity and high sensitivity. And it's interesting that other amines did not interfere with the recognition between L and 1,3-diaminopropane. The proposed sensing mechanism was supported by Job's plots, ¹H NMR titration, FT-IR, electron-spray ionization, and density functional theory calculation analysis. The limits of detection were estimated as 1.34 × 10⁻⁸ M. The self-made test strips and silica gel plates realized the easy detection of 1, 3-diaminopropane. L-1, 3-diaminopropane possessed the potential for fingerprint recognition based on AIEE in the silica gel plates developed within this study. Notably, bioimaging in seeds, plant tissues, Caenorhabditis elegans, and mice revealed that L could be suitable as an effective sensor for detecting 1, 3-diaminopropane in living systems with the strong “turn-on” fluorescence. Importantly, L showed good biocompatibility and could effectively recognize 1, 3-diaminopropane and reveal its location with colored AIEE fluorescence in HeLa cells.

多胺在人体中起重要作用。在这里，方便地合成AIE材料2-（吡喃-1-基亚甲基）丙二腈（L）能够荧光识别气液固三相中的1，3-二氨基丙烷，具有良好的选择性和高灵敏度。有趣的是，其他胺类不会干扰L与1,3-二氨基丙烷之间的识别。乔布斯图，¹ H NMR滴定，FT-IR，电子喷雾电离和密度泛函理论计算分析为拟议的传感机制提供了支持。估计的检测限为1.34×10 ^-8M  。自制的测试条和硅胶板实现了1,3-二氨基丙烷的简便检测。大号在本研究开发的硅胶板中，-1，3-二氨基丙烷具有基于AIEE的指纹识别潜力。值得注意的是，在种子，植物组织，秀丽隐杆线虫和小鼠中的生物成像显示，L可能适合作为具有强“开启”荧光的生物系统中检测1，3-二氨基丙烷的有效传感器。重要的是，L具有良好的生物相容性，可以有效识别1,3-二氨基丙烷，并在HeLa细胞中以有色的AIEE荧光显示其位置。