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Intraobserver and interobserver agreement among anterior chamber angle evaluations using automated 360-degree gonio-photos.
PLOS ONE ( IF 3.7 ) Pub Date : 2021-05-06 , DOI: 10.1371/journal.pone.0251249
Masato Matsuo 1 , Shiro Mizoue 2 , Koji Nitta 3 , Yasuyuki Takai 1 , Kazunobu Sugihara 1 , Masaki Tanito 1
Affiliation  

PURPOSE To investigate the reproducibility for the iridocorneal angle evaluations using the pictures obtained by a gonioscopic camera, Gonioscope GS-1 (Nidek Co., Gamagori, Japan). METHODS The pragmatic within-patient comparative diagnostic evaluations for 140 GS-1 gonio-images obtained from 35 eyes of 35 patients at four ocular sectors (superior, temporal, inferior, and nasal angles) were conducted by five independent ophthalmologists including three glaucoma specialists in a masked fashion twice, 1 week apart. We undertook the observer agreement and correlation analyses of Scheie's angle width and pigmentation gradings and detection of peripheral anterior synechia and Sampaolesi line. RESULTS The respective Fleiss' kappa values for the four elements between manual gonioscopy and automated gonioscope by the glaucoma specialist were 0.22, 0.40, 0.32 and 0.58. Additionally, the respective intraobserver agreements for the four elements by the glaucoma specialist each were 0.32 to 0.65, 0.24 to 0.71, 0.35 to 0.70, and 0.20 to 0.76; the Fleiss' kappa coefficients for the four elements among the three glaucoma specialists were, respectively, 0.31, 0.38, 0.31, and 0.17; the Fleiss' kappa coefficients for the angle width and pigmentation gradings between the two glaucoma specialists each were 0.30 to 0.35, and 0.29 to 0.43, respectively. Overall, the Kendall's tau coefficients for the angle gradings reflected the positive correlations in the evaluations. CONCLUSION Our findings suggested slight-to-substantial intraobserver agreement and slight-to-fair (among the three) or fair-to-moderate (between the two each) interobserver agreement for the angle assessments using GS-1 gonio-photos even by glaucoma specialists. Sufficient training and a solid consensus should allow us to perform more reliable angle assessments using gonio-photos with high reproducibility.

中文翻译:

使用自动 360 度角照片评估前房角之间的观察者内和观察者间的一致性。

目的 使用由房角镜相机 Gonioscope GS-1(Nidek Co., Gamagori, Japan)获得的图片研究虹膜角膜角评估的可重复性。方法 对从 35 名患者的 35 只眼在四个眼部(上角、颞角、下角和鼻角)获得的 140 张 GS-1 前角图像进行实用的患者内比较诊断评估,由五名独立眼科医生进行,其中包括三名青光眼专家。两次蒙面时装,间隔 1 周。我们对Scheie 角宽度和色素沉着分级以及周边前粘连和Sampaolesi 线的检测进行了观察者一致性和相关性分析。结果 青光眼专家手动前房角镜检查和自动前房角镜检查之间四个元素的 Fleiss kappa 值为 0.22,0.40、0.32 和 0.58。此外,青光眼专家对四个要素的观察者内一致性分别为 0.32 至 0.65、0.24 至 0.71、0.35 至 0.70 和 0.20 至 0.76;三位青光眼专家的四种元素的Fleiss kappa系数分别为0.31、0.38、0.31和0.17;两位青光眼专家之间的角宽度和色素沉着分级的 Fleiss kappa 系数分别为 0.30 至 0.35 和 0.29 至 0.43。总体而言,角度分级的 Kendall tau 系数反映了评估中的正相关性。结论 我们的研究结果表明,即使是青光眼,使用 GS-1 侧角照片进行角度评估时,观察者内部一致性和轻微到公平(三者之间)或公平到中等(两者之间)的观察者间一致性专家。足够的培训和坚实的共识应该使我们能够使用具有高度可重复性的测角照片进行更可靠的角度评估。
更新日期:2021-05-06
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