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Future stroke risk in the chronic phase of post-percutaneous coronary intervention.
PLOS ONE ( IF 3.7 ) Pub Date : 2021-05-06 , DOI: 10.1371/journal.pone.0251253
Shinsuke Muraoka 1 , Daiki Somiya 1 , Aoi Ebata 1 , Yuki Kumagai 1 , Naoki Koketsu 1
Affiliation  

A percutaneous coronary intervention (PCI) is widely performed for acute coronary syndromes or chronic coronary syndromes. Periprocedural stroke is a clinically significant complication during PCI. The incidence of cerebrovascular events (CVEs) after PCI in the chronic phase is obscure. This study aimed to investigate the prevalence of CVEs after PCI in the chronic phase and evaluate the usefulness of a simple coronary artery calcification (CAC) evaluation method. This prospective observational study included 179 patients who underwent PCI between January 2016 and December 2018. The incidence of cerebral infarction was examined from one month after PCI to December 2019. In total, 171 individuals (134 men; mean age, 69.8 ± 9.8 years) were recruited. During a median follow-up period of 33 months, the onset of cerebral infarction was observed in 20 individuals (11.7%). More CAC sites (p = 0.009) and post-PCI for the chronic coronary syndrome (p = 0.049) showed a significant association with future CVEs. There was no significant cervical internal carotid artery stenosis for patients who occurred CVEs. The cutoff value for the number of CAC sites for predicting future CVEs was 4.5. The new and easy method accurately reflected future CVEs risk and may be clinically applicable.

中文翻译:

经皮冠状动脉介入治疗慢性期的未来卒中风险。

经皮冠状动脉介入治疗 (PCI) 广泛用于急性冠状动脉综合征或慢性冠状动脉综合征。围手术期卒中是 PCI 期间具有临床意义的并发症。慢性期 PCI 后脑血管事件 (CVE) 的发生率尚不清楚。本研究旨在调查慢性期 PCI 后 CVE 的患病率,并评估简单冠状动脉钙化 (CAC) 评估方法的有效性。这项前瞻性观察性研究纳入了 2016 年 1 月至 2018 年 12 月期间接受 PCI 的 179 名患者。从 PCI 后一个月至 2019 年 12 月检查了脑梗塞的发生率。总共有 171 人(134 名男性;平均年龄,69.8 ± 9.8 岁)被招募。在 33 个月的中位随访期内,在 20 人(11.7%)中观察到脑梗塞的发作。更多的 CAC 位点 (p = 0.009) 和 PCI 后慢性冠状动脉综合征 (p = 0.049) 显示出与未来 CVE 的显着关联。发生CVEs的患者没有明显的颈内动脉狭窄。用于预测未来 CVE 的 CAC 站点数量的截止值为 4.5。这种新的简单方法准确地反映了未来的 CVE 风险,并且可能在临床上适用。
更新日期:2021-05-06
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