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Plant Pan-Genomics Comes of Age.
Annual Review of Plant Biology ( IF 23.9 ) Pub Date : 2021-04-13 , DOI: 10.1146/annurev-arplant-080720-105454
Li Lei 1 , Eugene Goltsman 1 , David Goodstein 1 , Guohong Albert Wu 1 , Daniel S Rokhsar 1, 2 , John P Vogel 1, 3
Affiliation  

A pan-genome is the nonredundant collection of genes and/or DNA sequences in a species. Numerous studies have shown that plant pan-genomes are typically much larger than the genome of any individual and that a sizable fraction of the genes in any individual are present in only some genomes. The construction and interpretation of plant pan-genomes are challenging due to the large size and repetitive content of plant genomes. Most pan-genomes are largely focused on nontransposable element protein coding genes because they are more easily analyzed and defined than noncoding and repetitive sequences. Nevertheless, noncoding and repetitive DNA play important roles in determining the phenotype and genome evolution. Fortunately, it is now feasible to make multiple high-quality genomes that can be used to construct high-resolution pan-genomes that capture all the variation. However, assembling, displaying, and interacting with such high-resolution pan-genomes will require the development of new tools. Expected final online publication date for the Annual Review of Plant Biology, Volume 72 is May 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

中文翻译:

植物泛基因组学时代的来临。

全基因组是物种中基因和/或DNA序列的非冗余集合。大量研究表明,植物全基因组通常比任何个体的基因组都要大得多,并且任何个体中相当大一部分的基因仅存在于某些基因组中。植物全基因组的构建和解释由于植物基因组的大尺寸和重复性内容而具有挑战性。大多数泛基因组主要集中于不可转座元素蛋白质编码基因,因为与非编码和重复序列相比,它们更容易分析和定义。然而,非编码和重复的DNA在决定表型和基因组进化中起着重要的作用。幸运的是,现在可行的是制作多个高质量基因组,这些基因组可用于构建捕获所有变异的高分辨率全基因组。但是,组装,展示此类高分辨率泛基因组并与之交互将需要开发新工具。《植物生物学年度评论》第72卷的最终最终在线发布日期为2021年5月。有关修订的估算,请参见http://www.annualreviews.org/page/journal/pubdates。
更新日期:2021-04-13
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