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Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos.
Protein & Cell ( IF 21.1 ) Pub Date : 2021-04-01 , DOI: 10.1007/s13238-021-00824-z
Yu Wei 1, 2 , Yingsi Zhou 1 , Yajing Liu 1 , Wenqin Ying 1 , Ruiming Lv 1 , Qimeng Zhao 1, 2 , Haibo Zhou 1, 3 , Erwei Zuo 4 , Yidi Sun 1 , Hui Yang 1, 3 , Changyang Zhou 1
Affiliation  



中文翻译:

CRISPR-Cas12a的不分皂白的ssDNA切割活性不会在小鼠胚胎中引起可检测到的脱靶效应。

更新日期:2021-04-01
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