Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2.,Protein & Cell

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Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2.
Protein & Cell ( IF 21.1 ) Pub Date : 2021-03-26 , DOI: 10.1007/s13238-021-00832-z
Dan Zhao ₁ , Weifan Xu _{2,

3} , Xiaofan Zhang ₁ , Xiaoting Wang ₄ , Yiyue Ge ₅ , Enming Yuan ₁ , Yuanpeng Xiong ₆ , Shenyang Wu ₇ , Shuya Li ₁ , Nian Wu ₁ , Tingzhong Tian ₁ , Xiaolong Feng ₈ , Hantao Shu ₁ , Peng Lang ₁ , Jingxin Li ₅ , Fengcai Zhu _{5,

9} , Xiaokun Shen ₁₀ , Haitao Li _{3,

11} , Pilong Li _{2,

3} , Jianyang Zeng ₁

Affiliation

Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, 100084, China.
Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, 100084, China.
Silexon AI Technology Co., Ltd, Nanjing, 210033, China.
NHC Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, 210009, China.
Bioinformatics Division, BNRIST/Department of Computer Science and Technology, Tsinghua University, Beijing, 100084, China.
Protein Preparation and Identification Facility, Technology Center for Protein Science, Tsinghua University, Beijing, 100084, China.
Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430074, China.
Center for Global Health, Nanjing Medical University, Nanjing, 210009, China.
Convalife (Shanghai) Co., Ltd, Shanghai, 201203, China.
Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center for Biological Structure, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing, 100084, China.