Long-standing theories of borderline personality disorder (BPD) suggest that symptoms develop at least in part from childhood adversity. Emotion dysregulation may meaningfully mediate these effects. The current study examined three factors related to emotion dysregulation-alexithymia, affective lability, and impulsivity-as potential mediators of the relation between childhood adversity and BPD diagnosis in 101 individuals with BPD and 95 healthy controls. Path analysis compared three distinct models informed by the literature. Results supported a complex mediation model wherein (a) alexithymia partially mediated the relation of childhood adversity to affective lability and impulsivity; (b) affective lability mediated the relation of childhood adversity to BPD diagnosis; and (c) affective lability and impulsivity mediated the relation of alexithymia to BPD diagnosis. Findings suggest that affective lability and alexithymia are key to understanding the relationship between childhood adversity and BPD. Interventions specifically targeting affective lability, impulsivity, and alexithymia may be particularly useful for this population.

中文翻译：

---

边缘性人格障碍的情感障碍，情感能力，冲动和儿童逆境。

边缘性人格障碍（BPD）的长期理论表明，症状至少部分源于儿童期的逆境。情绪失调可能有意义地介导了这些影响。本研究调查了101名BPD患者和95名健康对照者中与情绪失调，肢体发育不全，情感不稳定和冲动有关的三个因素，这些因素是儿童逆境与BPD诊断之间关系的潜在媒介。路径分析比较了文献提供的三种不同模型。结果支持一个复杂的调解模型，其中（a）智力障碍部分地介导了儿童逆境与情感不稳定和冲动的关系；（b）情感不稳定性介导了儿童逆境与BPD诊断的关系；（c）情感不稳定和冲动介导了运动障碍与BPD诊断的关系。研究结果表明，情感不稳定和读写障碍是理解儿童逆境与BPD之间关系的关键。专门针对情感不稳定性，冲动性和运动障碍的干预措施可能对该人群特别有用。