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Three is a crowd: Clinical outcomes of a twice daily versus a thrice daily metronidazole dosing strategy from a multicenter study
Anaerobe ( IF 2.3 ) Pub Date : 2021-05-07 , DOI: 10.1016/j.anaerobe.2021.102378
Sunish Shah 1 , Kathleen Adams 2 , Jacob Merwede 3 , Dayna McManus 4 , Jeffrey Topal 5
Affiliation  

This was a multicenter, retrospective study of patients with anaerobic bacteremia comparing metronidazole 500 mg every 8 h versus 500 mg every 12 h. Of 782 patients reviewed, 85 met inclusion criteria. There was no significant difference in mortality, length of stay, or escalation of therapy between dosing strategies.



中文翻译:

三是人群:来自多中心研究的每日两次与每日三次甲硝唑给药策略的临床结果

这是一项针对厌氧菌血症患者的多中心回顾性研究,比较甲硝唑每 8 小时 500 毫克与每 12 小时 500 毫克。在审查的 782 名患者中,85 名符合纳入标准。给药策略之间的死亡率、住院时间或治疗升级没有显着差异。

更新日期:2021-05-07
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