In capacitive transducers area, the fabrication process variations in the parameters that define the nominal capacitance induce mismatch between the fabricated transductors; and in order to minimize it a new frontend architecture, that does not need a reference sensor for calibration, is presented here. The proposed system works with a DC reference signal, instead of an AC signal as most of the reported works. A readout system using the proposed architecture was designed in a 180nm CMOS technology for a particular capacitive microfluidic bio-sensor to detect E.Coli bacteria. The nominal sensor has a capacitance range that goes from 192pF to 122 pF for a 0-100,000 UFC/ml concentration range.

中文翻译：

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电容式生物传感器的自校准读数前端

在电容式换能器领域，定义标称电容的参数的制造工艺变化会引起制造的换能器之间的失配；为了使它最小化，这里提出了一种新的前端架构，该架构不需要参考传感器进行校准。所建议的系统使用DC参考信号，而不是大多数报告的工作采用AC信号。使用提议的体系结构的读出系统是在180nm CMOS技术中设计的，用于特定的电容微流体生物传感器来检测大肠杆菌。对于0-100,000 UFC / ml的浓度范围，标称传感器的电容范围从192pF到122pF。