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Iso-octenidine: Promising Octenidine Analogue with Improved Solubility
Current Organic Synthesis ( IF 1.8 ) Pub Date : 2021-07-31 , DOI: 10.2174/1570179417666201231104453
Igor K Yakuschenko 1 , Nataliya N Pozdeeva 1 , Viktoriya A Mumyatova 1 , Alexey A Terentiev 1 , Svyatoslav Ya Gadomsky 1
Affiliation  

Iso-octenidine, an isomer of octenidine dihydrochloride, was synthesized and studied for the first time. Iso-octenidine was demonstrated to be 3-fold more soluble in water in comparison to original octenidine, and both substances had remarkably similar antibacterial activity (tested on Escherichia Coli and Micrococcus luteus).



中文翻译:

异奥替尼啶:具有改善溶解度的有前景的奥替尼啶类似物

首次合成并研究了奥替尼啶二盐酸盐的异构体异奥替尼啶。与原来的奥替尼啶相比,异奥替尼啶被证明在水中的溶解度是原来的 3 倍,并且两种物质具有非常相似的抗菌活性(在大肠杆菌和藤黄微球菌上测试)。

更新日期:2021-08-30
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