High-intensity focused ultrasound (HIFU) is a non-invasive method of ablating malignant tumors. This paper will review the current clinical application of HIFU specially in the treatment of breast cancer. In addition to clinical studies, this review will also look into some basic studies that could address the technical issues related to this modality. In general, HIFU is considered to be safe being non-invasive and non-ionizing. The complication occurrence rate is low and repeated treatment is possible, making it an attractive option for some patients. However, for more than two decades since it was first used to treat breast cancer, clinical studies on HIFU still remain at the investigative stage and are only available in several centers. Reasons contributing to such few studies on HIFU include lack of specialized medical team and bioengineering technical staff, and breast cancer-dedicated imaging-HIFU platform to attain positive outcomes. Despite these circumstances, we believe that HIFU will eventually become the treatment of choice for most breast cancer patients in the near future.

高强度聚焦超声（HIFU）是一种消融恶性肿瘤的非侵入性方法。本文就目前HIFU在乳腺癌治疗中的临床应用作一综述。除了临床研究外，本综述还将研究一些可以解决与这种模式相关的技术问题的基础研究。一般来说，HIFU 被认为是安全的非侵入性和非电离。并发症发生率低，可以重复治疗，对一些患者来说是一个有吸引力的选择。然而，自从首次用于治疗乳腺癌以来，HIFU 的临床研究仍处于研究阶段，仅在几个中心可用。导致 HIFU 研究很少的原因包括缺乏专业的医疗团队和生物工程技术人员，以及乳腺癌专用成像-HIFU 平台以获得积极成果。尽管存在这些情况，我们相信 HIFU 最终将在不久的将来成为大多数乳腺癌患者的首选治疗方法。