Given the major role played by sleep in the particular relationship between suicidality and major depression, the aim of this study was to empirically identify polysomnographic markers specific to suicidal ideation in major depressed individuals in order to allow better suicide prevention in this high-risk subpopulation. Demographic and polysomnographic data from 190 individuals (34 healthy controls and 156 untreated unipolar major depressed individuals) recruited from the sleep laboratory database were analysed. Suicidal ideation were considered present if the score in item G of the Beck Depression Inventory was ≥1 and/or if they were highlighted during the systematic psychiatric assessment conducted on admission to the sleep laboratory. Independently of depression severity, major depressed individuals with suicidal ideation present a decrease in deep NREM sleep (slow-wave sleep) and an increase in light NREM sleep (stage 1 + stage 2) compared to those without suicidal ideation. There are no significant differences for the other polysomnographic parameters. In our study, we highlighted the existence of potential polysomnographic markers of suicidal ideation in untreated unipolar major depressed individuals, which seems to open up new perspectives for the identification and management of individuals at high-risk of suicide in this particular subpopulation.

鉴于睡眠在自杀和重性抑郁之间的特定关系中所起的主要作用，本研究的目的是根据经验确定重度抑郁症患者自杀意念特有的多导睡眠图标记，以便在这一高危人群中更好地预防自杀。分析了从睡眠实验室数据库中招募的 190 名个体（34 名健康对照者和 156 名未经治疗的单相重度抑郁症患者）的人口统计学和多导睡眠图数据。如果贝克抑郁量表的 G 项得分≥1 和/或在进入睡眠实验室时进行的系统精神病学评估中突出显示，则认为存在自杀意念。独立于抑郁症的严重程度，与没有自杀意念的人相比，有自杀意念的重度抑郁症患者的深度 NREM 睡眠（慢波睡眠）减少，而轻度 NREM 睡眠（第 1 阶段 + 阶段 2）增加。其他多导睡眠图参数没有显着差异。在我们的研究中，我们强调了未经治疗的单极重度抑郁症个体存在潜在的自杀意念多导睡眠图标记，这似乎为识别和管理这一特定亚群中的高自杀风险个体开辟了新的视角。