RNA modifications constitute an essential layer of gene regulation in living organisms. As the most prevalent internal modification on eukaryotic mRNAs, N⁶-methyladenosine (m⁶A) exists in many plant species and requires the evolutionarily conserved methyltransferases, demethylases, and m⁶A binding proteins for writing, erasing, and reading m⁶A, respectively. In plants, m⁶A affects many aspects of mRNA metabolism, including alternative polyadenylation, secondary structure, translation, and decay, which underlies various plant developmental processes and stress responses. Here, we discuss the recent progress in understanding the roles of m⁶A modification in mRNA metabolism and their mechanistic link with plant development and stress responses. We also highlight some outstanding questions and provide an outlook on future prospects of m⁶A research in plants.

RNA 修饰构成了生物体中基因调控的基本层。作为真核 mRNA 最普遍的内部修饰，N ⁶ -甲基腺苷 (m ⁶ A) 存在于许多植物物种中，需要进化上保守的甲基转移酶、去甲基化酶和 m ⁶ A 结合蛋白来写入、擦除和读取 m ⁶ A，分别。在植物中，m ⁶ A 影响 mRNA 代谢的许多方面，包括替代多聚腺苷酸化、二级结构、翻译和衰变，这是各种植物发育过程和应激反应的基础。在这里，我们讨论了在理解 m ⁶的作用方面的最新进展mRNA 代谢的修饰及其与植物发育和应激反应的机制联系。我们还强调了一些悬而未决的问题，并对植物中 m ⁶ A 研究的未来前景进行了展望。