At present, the treatment for moyamoya disease (MMD) primarily consists of combined direct and indirect bypass surgery. Nevertheless, more than half of indirect bypass surgeries fail to develop good collaterals from the dura and temporal muscle. This study aimed to investigate whether microRNAs (miRNAs) in cerebrospinal fluid (CSF) could serve as biomarkers for the prediction of postoperative collateral formation.

中文翻译：

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在脑脊液中使用一组四种 microRNA 作为烟雾病术后新血管生成的预测生物标志物

目前，烟雾病（MMD）的治疗主要包括直接和间接联合搭桥手术。然而，超过一半的间接搭桥手术未能从硬脑膜和颞肌中形成良好的侧支循环。本研究旨在调查脑脊液 (CSF) 中的 microRNA (miRNA) 是否可以作为预测术后侧支形成的生物标志物。