Wenbin Gong, Kun Guo, Tao Zheng, Miao Fang, Haohao Xie, Weijie Li, Zhiwu Hong, Huajian Ren, Guosheng Gu, Gefei Wang, Zhiming Wang, Xiuwen Wu, and Jianan Ren. 2020. Preliminary exploration of the potential of spliceosome‐associated protein 130 for predicting disease severity in Crohn's disease. Ann. N.Y. Acad. Sci. 1462: 128–138.

A reader contacted the journal about a nomenclature confusion that the authors have agreed needs to be corrected:

Corrected title: Preliminary exploration of the potential of splicing factor 3b subunit 3 for predicting disease severity in Crohn's disease.

Corrected first sentence of the abstract: The role of splicing factor 3b subunit 3 (SF3B3) (also known as SAP130) in gut inflammation, particularly in Crohn's disease (CD), remains unclear.

Corrected first sentence of the second paragraph on p. 128: Splicing factor 3b subunit 3 (SF3B3) (which has been referred to as spliceosome‐associated protein 130 (SAP130) in some publications), a component of the U2 small nuclear ribonucleoprotein–associated protein complex located in the nucleus in normal live cells, is released to the extracellular milieu from dying cells as a type of DAMP.^10,11

Corrected last two sentences of the paragraph before the heading Immunohistochemistry on page 131: Primer sequences (SAP130: forward GCCATTCATGGAAACTTTTCTGG, reverse GTGAGTAGGGTATGTACTTTGCC) were designed using Primer Express software, v.3.0 (Applied Biosystems). Results were normalized using ACTB gene expression and shown as the relative expression value.

Corrected Figure 3B.

Corrected legend for Figure 3: (A) Immunofluorescence staining for SAP130 in active CD colon tissue (CD versus controls, n = 12/group). White arrows indicate SAP130 released from cell nuclei. White scale bar = 100 μm. (B) The mRNA levels of SAP130 in colon tissue of active CD versus controls by quantitative real‐time PCR (n = 6/group). (C and D) Immunohistochemical staining for Mincle in active CD colon tissue (CD versus controls, n = 8/group). Red arrows indicate Mincle‐positive cells. Black scale bar = 100 μm. Data are shown as mean values ± SEM. ^*P < 0.05; ^***P < 0.001 (unpaired t‐test).

The authors apologize for the confusion about the correct nomenclature.

龚文斌，郭坤，陶铮，苗iao，谢浩浩，李伟杰，洪志武，任华建，顾国胜，王戈飞，王志明，吴秀文和任建安。2020年。初步研究剪接体相关蛋白130预测克罗恩病严重程度的潜力。安 纽约学院 科学。1462：128–138。

一位读者联系了该期刊，以了解作者同意需要更正的术语混淆：

更正标题：剪接因子3b亚基3预测克罗恩病严重程度的潜力的初步探索。

摘要的第一句话已更正：剪接因子3b亚基3（SF3B3）（也称为SAP130）在肠道炎症，尤其是克罗恩病（CD）中的作用尚不清楚。

更正了第二段第1页的第一句。128：剪接因子3b亚基3（SF3B3）（在某些出版物中被称为剪接体相关蛋白130（SAP130）），是位于正常活细胞核中的U2小核糖核蛋白相关蛋白复合物的组成部分作为一种DAMP，它从垂死的细胞释放到细胞外环境中。^10,11

更正了第131页免疫组织化学标题之前的最后两个句子：使用Primer Express软件v.3.0（应用生物系统公司）设计了引物序列（SAP130：正向GCCATTCATGGAAACTTTTCTGG，反向GTGAGTAGGGTATGTACTTTGCC）。使用ACTB基因表达将结果标准化，并显示为相对表达值。

更正了图3B。

纠正了图3的图例：（A）活性CD结肠组织中CD130的免疫荧光染色（CD与对照组相比，n = 12 /组）。白色箭头指示从细胞核释放的SAP130。白色比例尺= 100μm。（B）通过定量实时PCR（n = 6 /组），活性CD结肠组织中SAP130的mRNA水平与对照相比。（C和D）在活跃的CD结肠组织中Mincle的免疫组织化学染色（CD与对照组相比，n = 8 /组）。红色箭头表示Mincle阳性细胞。黑色比例尺= 100μm。数据显示为平均值±SEM。^* P <0.05；^*** P <0.001（未配对t检验）。

作者对正确命名的困惑深表歉意。