Banana fusarium wilt caused by Fusarium. oxysporum f.sp. cubense race 4, has already become one of the main diseases in banana production. Previous research suggests that Foc can secrete two phytotoxins, respectively, fusaric acid and beauvericin, to contribute to its pathogenicity when it infects bananas. A gene cluster FUB consisting of 12 genes has been identified for fusaric acid biosynthesis in several Fusarium spp, including Fusarium. oxysporum f.sp. cubense race 4, F. oxysporum f.sp. lycopersici etc. In the present study, using reverse genetic research methods, we report the evidence for the kynurenine pathway as alternative biosynthetic pathways of fusaric acid in F. oxysporum f.sp. cubense 4. In the meanwhile, our experiments suggests that the beauvericin might not directly contribute to the pathogenicity to banana of F. oxysporum f.sp. cubense 4.

香蕉枯萎病由镰刀菌引起。oxysporum f.sp. 立方体4族已经成为香蕉生产中的主要疾病之一。先前的研究表明，Foc在感染香蕉时可以分泌两种植物毒素，分别为富沙酸和双链菌素，从而有助于其致病性。已经确定了由12个基因组成的基因簇FUB，可用于镰刀菌属（包括镰刀菌）中的镰刀菌酸生物合成。oxysporum f.sp. 立方体种族4，F.oxysporum f.sp. lycopersici在本研究中，使用反向遗传研究方法，我们报告了犬尿氨酸途径作为草酸镰刀菌中富沙酸的替代生物合成途径的证据。香蕉枯萎病4，同时，我们的实验表明，白僵菌可能不会直接有助于致病性的香蕉尖孢镰刀菌病菌 立方4。