Reactions are discussed that lead to the valuable amine functional group in aromatics and heteroaromatics, carried out under sustainable conditions in water enabled by micellar catalysis. These new technologies are general and have been successfully applied to intermediates associated with several targets in the pharmaceutical space. Each relies on ppm levels of Pd used either as solubilized catalysts or on the surface of easily formed nanoparticles. These processes also feature opportunities for recycling of the aqueous medium, thereby overall, offering greener, environmentally responsible methods for introducing nitrogen-containing functionality into organic molecules.

讨论了导致芳烃和杂芳烃中有价值的胺官能团的反应，这些反应在胶束催化下在水中可持续条件下进行。这些新技术是通用的，并已成功应用于与制药领域多个目标相关的中间体。每个都依赖于用作增溶催化剂或容易形成的纳米粒子表面的 Pd 的 ppm 水平。这些过程还具有回收水性介质的机会，因此总体而言，提供了将含氮官能团引入有机分子的更环保、对环境负责的方法。