Next-generation sequencing (NGS) has enabled fast, high-throughput nucleotide sequencing and has begun to be implemented into clinical practice for genomic-guided precision medicine in various cancer types. This review will discuss recent evidence that highlights opportunities for NGS to improve outcomes in sarcomas that have complex genomic profiles with no known driver mutations.

中文翻译：

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用于治疗无已知驱动突变的肉瘤的新一代测序。

新一代测序（NGS）实现了快速、高通量的核苷酸测序，并已开始应用于各种癌症类型的基因组引导精准医疗的临床实践。这篇综述将讨论最近的证据，这些证据强调了 NGS 改善肉瘤预后的机会，这些肉瘤具有复杂的基因组谱，且没有已知的驱动突变。