当前位置：
X-MOL 学术
›
J. X-Ray Sci. Technol.
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Stereotactic body radiation therapy for non-small cell lung cancer using the non-coplanar radiation of Cyberknife and Varian linac
Journal of X-Ray Science and Technology ( IF 3 ) Pub Date : 2021-04-29 , DOI: 10.3233/xst-210867 Wencheng Shao 1, 2 , Ziyin Chen 3 , Yanchun Bai 3 , Bingchen Xu 4 , Lili Xu 3 , Qiushuang Zhao 3 , Yang Wang 5 , Xiaobin Tang 1
Journal of X-Ray Science and Technology ( IF 3 ) Pub Date : 2021-04-29 , DOI: 10.3233/xst-210867 Wencheng Shao 1, 2 , Ziyin Chen 3 , Yanchun Bai 3 , Bingchen Xu 4 , Lili Xu 3 , Qiushuang Zhao 3 , Yang Wang 5 , Xiaobin Tang 1
Affiliation
PURPOSE:This study aims to evaluate the planned dose of stereotactic body radiation therapy (SBRT) for treating early peripheral non-small cell lung cancer (NSCLC) using the non-coplanar radiation from Cyberknife and Varian linac. Moreover, this study investigates whether Cyberknife and Varian linac are qualified for non-coplanar radiation SBRT for treating early peripheral NSCLC, and which one is better for protecting organs at risk (OARs). METHODS:Retrospective analysis was performed based on the Cyberknife radiation treatment plans (RTPs) and Varian Eclipse RTPs of 10 patients diagnosed with early peripheral NSCLC. The dose distributions in the target and OARs were compared between the RTPs of Cyberknife and Varian Eclipse using Mim medical imaging software. RESULTS:For PTV, no significant difference in D98 and D95 between the Cyberknife and Eclipse was observed (t = –0.35, –1.67, P > 0.05). The homogeneity indexes (HIs) of Cyberknife plans are higher (t = 71.86, P < 0.05) than those of Eclipse plans. The V10, V15, V20, V25, V30 and Dmean of the lung with NSCLC and the V20 of the whole lung for Cyberknife were less than those for Eclipse (t = –4.73, –5.62, –7.75, –6.38, –6.89, –3.14, –7.09, respectively, P < 0.05). Cyberknife plans have smaller spinal cord Dmax, trachea Dmax, heart Dmax, chest wall Dmax (t = –2.49, –2.57, –3.71, –3.56, respectively, P < 0.05) and esophagus Dmax (t = –1.95, P > 0.05) than Varian Eclipse plans. CONCLUSION:To fulfill SBRT by non-coplanar radiation, Cyberknife is recommended for the institutions equipped with Cyberknife, while Varian linac can be applied for the institutions that have not adopted Cyberknife in clinical radiotherapy yet.
中文翻译：
使用射波刀和瓦里安直线加速器的非共面辐射对非小细胞肺癌进行立体定向放射治疗
目的：本研究旨在评估使用射波刀和瓦里安直线加速器的非共面辐射治疗早期外周非小细胞肺癌 (NSCLC) 的立体定向放射治疗 (SBRT) 的计划剂量。此外，本研究调查了射波刀和瓦里安直线加速器是否有资格进行非共面辐射 SBRT 治疗早期外周 NSCLC，以及哪一种更适合保护高危器官 (OAR)。方法：基于射波刀放射治疗计划（RTPs）和Varian Eclipse RTPs对10例诊断为早期外周非小细胞肺癌患者进行回顾性分析。使用 Mim 医学成像软件比较了射波刀和 Varian Eclipse 的 RTP 在目标和 OAR 中的剂量分布。结果：对于 PTV，未观察到射波刀和 Eclipse 之间的 D98 和 D95 有显着差异（t = –0.35，–1.67，P > 0.05）。Cyberknife 计划的同质性指数 (HI) 高于 Eclipse 计划（t = 71.86，P < 0.05）。NSCLC的肺V10、V15、V20、V25、V30和Dmean以及射波刀的全肺V20均小于Eclipse（t = –4.73, –5.62, –7.75, –6.38, –6.89,分别为–3.14、–7.09，P < 0.05）。射波刀计划具有较小的脊髓 Dmax、气管 Dmax、心脏 Dmax、胸壁 Dmax（分别为 t = –2.49、–2.57、–3.71、–3.56，P < 0.05）和食道 Dmax（t = –1.95，P > 0.05 ) 比 Varian Eclipse 计划。结论：为实现非共面辐射SBRT，推荐安装射波刀的机构使用射波刀，
更新日期：2021-05-02
中文翻译：
使用射波刀和瓦里安直线加速器的非共面辐射对非小细胞肺癌进行立体定向放射治疗
目的：本研究旨在评估使用射波刀和瓦里安直线加速器的非共面辐射治疗早期外周非小细胞肺癌 (NSCLC) 的立体定向放射治疗 (SBRT) 的计划剂量。此外，本研究调查了射波刀和瓦里安直线加速器是否有资格进行非共面辐射 SBRT 治疗早期外周 NSCLC，以及哪一种更适合保护高危器官 (OAR)。方法：基于射波刀放射治疗计划（RTPs）和Varian Eclipse RTPs对10例诊断为早期外周非小细胞肺癌患者进行回顾性分析。使用 Mim 医学成像软件比较了射波刀和 Varian Eclipse 的 RTP 在目标和 OAR 中的剂量分布。结果：对于 PTV，未观察到射波刀和 Eclipse 之间的 D98 和 D95 有显着差异（t = –0.35，–1.67，P > 0.05）。Cyberknife 计划的同质性指数 (HI) 高于 Eclipse 计划（t = 71.86，P < 0.05）。NSCLC的肺V10、V15、V20、V25、V30和Dmean以及射波刀的全肺V20均小于Eclipse（t = –4.73, –5.62, –7.75, –6.38, –6.89,分别为–3.14、–7.09，P < 0.05）。射波刀计划具有较小的脊髓 Dmax、气管 Dmax、心脏 Dmax、胸壁 Dmax（分别为 t = –2.49、–2.57、–3.71、–3.56，P < 0.05）和食道 Dmax（t = –1.95，P > 0.05 ) 比 Varian Eclipse 计划。结论：为实现非共面辐射SBRT，推荐安装射波刀的机构使用射波刀，
京公网安备 11010802027423号