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PVA/gelatin-based hydrogel coating of nickel-titanium alloy for improved tissue-implant interface
Applied Physics A ( IF 2.7 ) Pub Date : 2021-04-28 , DOI: 10.1007/s00339-021-04542-5
G. M. Simsek , J. Barthes , C. Muller , G. B. McGuinness , N. E. Vrana , G. G. Yapici

Nickel-titanium shape memory alloys have attracted notable interest for biomedical applications due to their unique properties. However, there are still some concerns on the potential release of nickel ions causing adverse reactions in-vivo at high concentrations. In this work, samples were coated with a polyvinyl alcohol/gelatin hydrogel. Coating stability, corrosion resistance and biocompatibility were investigated. Coated samples exhibited similar shape memory response to that of the uncoated substrates in wire form. Additionally, the hydrogel coating led to a decrease in the surface temperature and significantly improved the corrosion resistance of the shape memory substrate. The presence of the hydrogel layer does not affect the biocompatibility of the alloy while providing a semi-degradable, hydrophilic surface that forms a cushion at the tissue-implant interfaces.



中文翻译:

镍钛合金的PVA /明胶基水凝胶涂层可改善组织与植入物的界面

镍钛形状记忆合金由于其独特的性能而引起了生物医学应用的极大兴趣。然而,在高浓度下,镍离子在体内可能引起不良反应的潜在释放仍存在一些问题。在这项工作中,样品涂有聚乙烯醇/明胶水凝胶。研究了涂层的稳定性,耐腐蚀性和生物相容性。涂覆的样品表现出与未涂覆的线材形式相似的形状记忆响应。另外,水凝胶涂层导致表面温度降低并且显着提高了形状记忆基板的耐腐蚀性。水凝胶层的存在不会影响合金的生物相容性,但会提供半降解性,

更新日期:2021-04-29
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