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Heuristic-based allocation of supply constrained blood platelets in emerging economies
Journal of Heuristics ( IF 2.7 ) Pub Date : 2021-04-28 , DOI: 10.1007/s10732-021-09474-0
Fredrik Ødegaard , Sudipendra Nath Roy

Platelets are valuable, but highly perishable, blood components used in the treatment of, among others, viral dengue fever, blood-related illness, and post-chemotherapy following cancer. Given the short shelf-life of 3–5 days and a highly volatile supply and demand pattern, platelet inventory allocation is a challenging task. This is especially prevalent in emerging economies where demand variability is more pronounced due to neglected tropical diseases, and a perpetual shortage of supply. The consequences of which have given rise to an illegal ‘red market’. Motivated by experience at a regional hospital in India, we investigate the problem of platelet allocation among three priority-differentiated demand streams. Specifically we consider a central hospital which, in addition to internal emergency and non-emergency requests, faces external demand from local clinics. We analyze the platelet allocation decision from a social planner’s perspective and propose an allocation heuristic based on revenue management (RM) principles. The objective is to maximize total social benefit in a highly supply-constrained environment. Using data from the aforementioned Indian hospital as a case study, we conduct a numerical simulation and sensitivity analysis to evaluate the allocation heuristic. The performance of the RM-based policy is evaluated against the current sequential first come, first serve policy and two fixed proportion-based rationing policies. It is shown that the RM-based policy overall dominates, serves patients with the highest medical urgency better, and can curtail patients’ need to procure platelets from commercial sources.



中文翻译:

新兴经济体基于启发式的供应受限血小板分配

血小板是宝贵的血液成分,但高度易腐烂,可用于治疗病毒登革热,血液相关疾病和癌症后的化学疗法等。鉴于3至5天的短保质期和高度波动的供需模式,血小板库存的分配是一项艰巨的任务。这在新兴经济体中尤为普遍,在这些新兴经济体中,由于忽略了热带病和长期供应不足,需求变化更加明显。其后果导致了非法的“红色市场”。基于印度一家地区医院的经验,我们调查了三个优先级差异化需求流之间的血小板分配问题。具体来说,我们考虑一家中心医院,除了内部紧急和非紧急请求外,面临当地诊所的外部需求。我们从社会计划者的角度分析血小板分配决策,并根据收入管理(RM)原则提出分配启发式方法。目标是在高度供应受限的环境中最大化总的社会效益。使用来自上述印度医院的数据作为案例研究,我们进行了数值模拟和敏感性分析,以评估分配启发式方法。基于RM的策略的性能是根据当前的先后顺序,先到先得策略和两个基于比例的固定比例分配策略进行评估的。结果表明,基于RM的政策总体上占主导地位,可以更好地为医疗紧急度最高的患者提供服务,并且可以减少患者从商业渠道购买血小板的需求。我们从社会计划者的角度分析血小板分配决策,并根据收入管理(RM)原则提出分配启发式方法。目标是在高度供应受限的环境中最大化总的社会效益。使用来自上述印度医院的数据作为案例研究,我们进行了数值模拟和敏感性分析,以评估分配启发式方法。基于RM的策略的性能是根据当前的先后顺序,先到先得策略和两个基于比例的固定比例分配策略进行评估的。结果表明,基于RM的政策总体上占主导地位,可以更好地为医疗紧急度最高的患者提供服务,并且可以减少患者从商业渠道购买血小板的需求。我们从社会计划者的角度分析血小板分配决策,并根据收入管理(RM)原则提出分配启发式方法。目标是在高度供应受限的环境中最大化总的社会效益。使用来自上述印度医院的数据作为案例研究,我们进行了数值模拟和敏感性分析,以评估分配启发式方法。基于RM的策略的性能是根据当前的先后顺序,先到先得策略和两个基于比例的固定比例分配策略进行评估的。结果表明,基于RM的政策总体上占主导地位,可以更好地为医疗紧急度最高的患者提供服务,并且可以减少患者从商业渠道购买血小板的需求。

更新日期:2021-04-29
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