Kinetic hydrate inhibitors (KHIs) have been used for over 25 years to prevent gas hydrate formation in oil and gas production flowlines. The main component in KHI formulations is a water-soluble polymer and most of these polymers are amide-based. A few polymaleamides were investigated as KHIs in the 1990 s. Since then, our knowledge of the optimal structural features for KHI polymers has improved. Here we report a more detailed KHI study on this class of polymers, demonstrating significant KHI performance enhancement. KHI experiments were conducted under high pressure with natural gas mixture in steel rocking cells using the slow (1 °C/h) constant cooling test method. The best polymaleamides gave T_o (av.) values at around 6.1 °C (Ca. ΔT = 14.0 °C) at the concentration of 2500 ppm. In addition, the best polymaleamides were compatible with 15 wt% (150,000 ppm) brines at up to 95 °C.

动力学水合物抑制剂（KHIs）已经使用了25年以上，以防止在油气生产流水线中形成天然气水合物。KHI配方中的主要成分是水溶性聚合物，其中大多数聚合物都是基于酰胺的。在1990年代，对一些聚马来酰胺作为KHI进行了研究。从那时起，我们对KHI聚合物最佳结构特征的了解得到了提高。在这里，我们报告了有关此类聚合物的更详细的KHI研究，表明了KHI性能的显着提高。使用慢速（1°C / h）恒定冷却测试方法在钢制摇摆室中用天然气混合物在高压下进行KHI实验。最好polymaleamides得到Ť _Ö（AV）的值在大约6.1℃（Ca中Δ Ť 浓度为2500 ppm时= 14.0°C）。此外，最好的聚马来酰胺在最高95°C的温度下可与15 wt％（150,000 ppm）的盐水相容。