The interaction of DNA with complexes of Zn(II) and 1,10-phenanthroline derivatives in aqueous salt solutions has been studied by the optical spectroscopy, fluorescence, and DNA melting methods. Bis-(1,10-phenanthroline)-(1,10-phenanthrocyanine)-dizinc (II) acetate (diZn) and its precursor, bis-(1,10-phenanthroline)-zinc (II) acetate (monoZn) have been used. The interaction of DNA with phenanthroline significantly differs from that with phenanthroline metal complexes. MonoZn and diZn form complexes with DNA. Depending on the molar ratio of the components, ligands may interact with DNA in several ways; one of these is presumably intercalation. No saturation binding was detected at 0.1 ≤ r ≤ 20 and 0.1 ≤ r ≤ 1.67 for monoZn and diZn, respectively. The formation of secondary complexes of monoZn and diZn with DNA is possible. The interaction with DNA leads to quenching the fluorescence of the metal complexes.

通过光谱，荧光和DNA熔融方法研究了DNA与Zn（II）和1,10-菲咯啉衍生物在盐水溶液中的配合物之间的相互作用。双-（1,10-菲咯啉）-（1,10-菲咯啉）-醋酸二锌（diZn）及其前体双-（1,10-菲咯啉）-醋酸锌（II）已被制成用过的。DNA与菲咯啉的相互作用与菲咯啉金属络合物的相互作用显着不同。MonoZn和diZn与DNA形成复合物。根据组分的摩尔比，配体可以几种方式与DNA相互作用。其中之一可能是插层。没有饱和结合以0.1≤检测ř ≤20和0.1≤ [R单锌和二锌分别≤1.67。单锌和二锌与DNA的二级络合物的形成是可能的。与DNA的相互作用导致金属配合物的荧光猝灭。