Abstract

Higher fungi represent a group of living organisms that remain poorly studied in terms of mycology and biochemistry. Among their secondary metabolites, toxic compounds are of particular interest, since they may be an etiological factor causing acute food intoxications, i.e., mycetismi. This review summarizes the information on the fungal species distributed in Russia and the toxicological properties of some of them as producers of simple nitrogen-containing compounds. The role of individual substances in toxidromes is discussed. The article considers a number of minor components that may have insignificant individual effects due to their low concentrations but may make a significant contribution to the modification of the toxic effect caused by a primary compound. A summary of data on new syndromes associated with toxins of higher fungi is presented. It was concluded that the combined effects of toxins can play an important role in intoxication with nitrogen-containing compounds.

中文翻译：

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高级真菌毒素的实际概念：简单的含氮化合物

摘要

高级真菌代表了一组在微生物学和生物化学方面仍研究不足的活生物体。在其次生代谢产物中，有毒化合物特别受关注，因为它们可能是引起急性食物中毒的病因，即霉菌病。这篇综述总结了有关分布在俄罗斯的真菌物种的信息，以及其中一些作为简单的含氮化合物的生产者的毒理学特性。讨论了各种物质在氧化反应中的作用。本文考虑了许多次要成分，由于它们的低浓度，它们可能没有明显的个体作用，但可能对改变由主要化合物引起的毒性作用做出了重大贡献。介绍了与高等真菌毒素相关的新综合症的数据摘要。结论是毒素的综合作用在含氮化合物中毒中起重要作用。