From the leaves of Ardisia quinquegona, two alkylated tetronic acid derivatives, named ardisiatetrons A and B (1, 2), and four triterpenoids (3–6) were isolated together with one known compound (7) by a combination of various kinds of chromatography. The structure of new methyl migrated triterpene (3) was confirmed by X-ray crystallographic analysis. Compounds 2, 3, and 7 showed moderate anti-Leishmania activity and cytotoxicity towards A549 cells.

Graphic abstract

中文翻译：

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Ardisiatetrons A和B：昆迪Ardisia quinquegona叶片中的四氢叶酸衍生物和三萜及其生物活性

从叶朱砂quinquegona，二烷基化的特窗酸衍生物，命名为ardisiatetrons A和B（1，2），和四个三萜类化合物（3 - 6）用一种已知化合物（一起分离7）通过各种色谱法的组合。通过X射线晶体学分析证实了新的甲基迁移的三萜（3）的结构。化合物2，3和7表现出中等抗利什曼原虫活性和细胞毒性对A549细胞。

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