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Influence of type of starch and feeding management on glycaemic control in diabetic dogs
Journal of Animal Physiology and Animal Nutrition ( IF 2.7 ) Pub Date : 2021-04-27 , DOI: 10.1111/jpn.13556
Eliana Teshima 1, 2 , Marcio Antonio Brunetto 3 , Fabio Alves Teixeira 3 , Márcia de Oliveira Sampaio Gomes 3 , Silvia Regina Ricci Lucas 3 , Gener Tadeu Pereira 1 , Aulus Cavalieri Carciofi 1
Affiliation  

The present study evaluated the effects of two diets with different starch sources and two feeding methods on the glycaemic control in dogs with diabetes mellitus. The diets had similar nutrient contents (40% starch and 16% dietary fibre), one formulated with 46% of broken rice and the other with 42% sorghum and 10% lentils (as-fed). Ten client-owned diabetic dogs were fed with each diet for 2 months, in a crossover design. Five dogs received NPH human insulin and food every 12 h (feeding method 1), and the other five received insulin every 12 h but were fed three times a day (feeding method 2). In feeding method 2, morning insulin was higher than the evening dose and dogs received the second meal after 4 to 5 h of the morning insulin and meal. Parameters evaluated included insulin dosage, 12- and 8-h glycaemic curves, complete blood count, biochemical profile and urinalysis. Glycaemic curves were analysed by ANOVA with repeated measures. Glycaemic control parameters (fasting, mean, minimum and maximum glycaemia and serum fructosamine) and glucose area under the curve (AUC) were calculated and analysed by paired t test (p < 0.05). In feeding method 1, dogs fed the sorghum-based diet presented lower mean (p = 0.04) and minimum blood glucose concentrations (p = 0.03), and a tendency to lower maximum blood glucose (p = 0.06) and glucose AUC (p = 0.08) than when fed the rice-based diet. When food was provided twice a day, the ingestion of the rice-based diet resulted in higher post-prandial glucose response than the diet with sorghum and lentil. In feeding method 2, there was no effect of diet on the assessed parameters (p > 0.05). No differences in insulin dosage were observed between groups or feeding methods (p > 0.05). Providing two meals a day followed by insulin administration associated with the sorghum- and lentil-based diet improved glycaemic control in diabetic dogs.

中文翻译:

淀粉种类和饲养管理对糖尿病犬血糖控制的影响

本研究评估了两种不同淀粉来源的饮食和两种喂养方法对糖尿病犬血糖控制的影响。日粮具有相似的营养成分(40% 淀粉和 16% 膳食纤维),一种含有 46% 的碎米,另一种含有 42% 的高粱和 10% 的扁豆(饲喂)。在交叉设计中,10 只客户拥有的糖尿病犬用每种饮食喂养 2 个月。五只狗每 12 小时接受一次 NPH 人胰岛素和食物(喂养方法 1),另外五只每 12 小时接受一次胰岛素,但每天喂养 3 次(喂养方法 2)。在喂养方法 2 中,早晨胰岛素高于晚上剂量,狗在早上胰岛素和餐后 4 至 5 小时后接受第二餐。评估的参数包括胰岛素剂量、12 小时和 8 小时血糖曲线、全血细胞计数、生化特征和尿液分析。血糖曲线通过重复测量的方差分析进行分析。血糖控制参数(空腹、平均、最小和最大血糖和血清果糖胺)和葡萄糖曲线下面积(AUC)通过配对计算和分析t检验 ( p  < 0.05)。在喂养方法 1 中,喂食高粱为基础的饮食的狗表现出较低的平均 ( p  = 0.04) 和最低血糖浓度 ( p  = 0.03),以及降低最大血糖 ( p  = 0.06) 和葡萄糖 AUC ( p  = 0.08)比喂食以大米为基础的饮食时。当每天提供两次食物时,以大米为基础的饮食比高粱和小扁豆饮食导致更高的餐后葡萄糖反应。在喂养方法 2 中,饮食对评估参数没有影响 ( p  > 0.05)。组间或喂养方法之间未观察到胰岛素剂量差异(p > 0.05)。每天提供两餐,然后以高粱和扁豆为基础的饮食相关的胰岛素给药改善了糖尿病犬的血糖控制。
更新日期:2021-04-27
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