Neuroticism has been associated with adverse cardiovascular health. Adverse cardiovascular health outcomes have also been linked to cardiovascular reactivity and cardiovascular reactivity habituation to acute psychosocial stress. As such, cardiovascular stress reactivity and habituation may be a factor in the association between neuroticism and disease risk. However, studies of the relationship between neuroticism and cardiovascular reactivity have produced mixed results. Moreover, the relationships between neuroticism, cardiovascular reactivity habituation, and general affect across a repeated stress paradigm have not been examined. The present study aimed to assess the relationships between neuroticism, positive and negative affect, and cardiovascular reactivity and habituation to acute psychosocial stress in a large, demographically diverse sample. Participants (N = 426) completed two 4-min mental arithmetic stressors, each with a separate baseline, in a single laboratory session while having discrete blood pressure and heart rate measurements taken. State positive and negative affect were measured immediately following informed consent, after receiving task instructions, and after each stress task. Trait neuroticism was measured using the Big Five Inventory. Each stress task elicited significant cardiovascular changes. Trait neuroticism was not significantly associated with cardiovascular reactivity or cardiovascular reactivity habituation, within or across stress tasks (all p's > 0.12). Across the entire study protocol, neuroticism was significantly related to lower positive affect and higher negative affect (both p's < 0.001). Trait neuroticism did not relate to stress-related cardiovascular adjustments but might confer a predisposition toward high negative affect.

神经质与不利的心血管健康有关。不利的心血管健康结果也与心血管反应性和心血管反应性对急性心理社会压力的习惯有关。因此，心血管应激反应和习惯可能是神经质和疾病风险之间关联的一个因素。然而，关于神经质和心血管反应性之间关系的研究产生了不同的结果。此外，尚未研究神经质、心血管反应性习惯和重复压力范式中的一般影响之间的关系。本研究旨在评估神经质、积极和消极情绪以及心血管反应性和对急性心理社会压力的习惯性之间的关系，人口统计多样化的样本。参加者（N  = 426) 完成了两个 4 分钟的心算压力源，每个都有一个单独的基线，在一次实验室会话中，同时进行了离散的血压和心率测量。在知情同意后、接受任务指示后和每次压力任务后立即测量状态的积极和消极影响。特质神经质是使用大五人格量表来衡量的。每项压力任务都会引起显着的心血管变化。特质神经质与压力任务内或跨压力任务的心血管反应性或心血管反应性习惯没有显着相关（所有p's > 0.12）。在整个研究方案中，神经质与较低的积极情绪和较高的消极情绪显着相关（p均< 0.001）。特质神经质与压力相关的心血管调整无关，但可能会导致产生高度负面影响的倾向。