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The PLASMA System for Transurethral Resection of the Prostate: A NICE Medical Technologies Guidance Update
Applied Health Economics and Health Policy ( IF 3.6 ) Pub Date : 2021-04-26 , DOI: 10.1007/s40258-021-00651-7
Laura Knight 1 , Susan Peirce 2 , Rhys Morris 1
Affiliation  

Lower urinary tract symptoms (LUTS) in men commonly occur as a consequence of benign prostatic hyperplasia (BPH), also known as prostate enlargement. Treatments for this can involve electrosurgical removal of a section of the prostate via transurethral resection of the prostate (TURP). This can be performed using either monopolar or bipolar electrosurgery. Bipolar TURP uses saline for irrigation rather than glycine, which drastically reduces the risk of TUR syndrome complications, thus allowing for increased procedure time if needed. The PLASMA system (formally known as TURis) is a bipolar TURP electrosurgery system used to treat LUTS secondary to BPH. National guidance recommending the use of TURis in the UK NHS was issued in 2014 by NICE and we now report the updated contribution from Cedar that was included in the update of that guidance for 2021. The evidence in this review suggests that the PLASMA system could be beneficial to patients in relation to hospitalisation and catheterisation time compared with monopolar TURP (mTURP). However, it appears to be comparable to mTURP for urological outcomes and worse for post-operative haematology outcomes such as decline in sodium and haemoglobin levels. Adverse events, however, occurred much less with PLASMA use.



中文翻译:

用于经尿道前列腺切除术的 PLASMA 系统:NICE 医疗技术指南更新

男性下尿路症状 (LUTS) 通常是良性前列腺增生 (BPH) 的结果,也称为前列腺肥大。对此的治疗可能包括通过经尿道前列腺切除术 (TURP) 电外科切除一部分前列腺。这可以使用单极或双极电外科进行。双极 TURP 使用盐水而不是甘氨酸进行冲洗,这大大降低了 TUR 综合征并发症的风险,从而在需要时增加了手术时间。PLASMA 系统(正式名称为 TURis)是一种双极 TURP 电外科系统,用于治疗继发于 BPH 的 LUTS。NICE 于 2014 年发布了推荐在英国 NHS 使用 TURis 的国家指南,我们现在报告 Cedar 的更新贡献,该贡献包含在 2021 年该指南的更新中。本综述中的证据表明 PLASMA 系统可以与单极 TURP (mTURP) 相比,在住院和导管插入时间方面对患者有益。然而,它在泌尿学结果方面似乎与 mTURP 相当,而在术后血液学结果方面则更糟,例如钠和血红蛋白水平的下降。然而,使用 PLASMA 时发生的不良事件要少得多。它在泌尿学结果方面似乎与 mTURP 相当,而在术后血液学结果方面则更糟,例如钠和血红蛋白水平的下降。然而,使用 PLASMA 时发生的不良事件要少得多。它在泌尿学结果方面似乎与 mTURP 相当,而在术后血液学结果方面则更糟,例如钠和血红蛋白水平的下降。然而,使用 PLASMA 时发生的不良事件要少得多。

更新日期:2021-04-27
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