The PIPA project is the first birth cohort study in Brazil focusing on the investigation of environmental pollutant exposure effects on child health. This program was developed in Rio de Janeiro, a highly urbanized city that encompasses a diversity of environmental and socioeconomic factors potentially harmful to human health. A pilot study was carried out between September 2017 and August 2018. This paper describes the socioeconomic environment and exposure pollutant profile of the PIPA pilot study population. The PIPA pilot study enrolled 139 pregnant women with a total of 135 (97%) births. Maternal blood (n = 139) and urine (n = 139) samples were collected between the 32nd and 38th weeks of pregnancy. Newborn umbilical cord blood (n = 125) and urine (n = 34) samples were collected at birth and during the 1st, 3rd, and 6th months of life (n = 132). Up to 75% of the study population reported a per capita income lower than US$200, 19% received governmental financial aid, and 21% were single mothers. At least 20% lived in low-income communities. Metals were observed above the limits of detection in 100% of the mother and newborn samples, while 48% and 23.5% showed detectable pyrethroid metabolite levels. Perfluoroalkyl acids were detected in approximately 80% of mother blood and urine samples and 70% of cord blood samples. At least one organochlorine compound was detected in approximately 30% of the newborn and mother samples. Pregnant women from poor communities in Rio de Janeiro and their children are exposed to several harmful pollutants.

PIPA项目是巴西的第一个出生队列研究，重点研究环境污染物暴露对儿童健康的影响。该计划是在里约热内卢开发的，里约热内卢是一个高度城市化的城市，涵盖了可能对人类健康有害的各种环境和社会经济因素。在2017年9月至2018年8月之间进行了一项试点研究。本文描述了PIPA试点研究人群的社会经济环境和暴露污染物概况。PIPA的先导研究招募了139名孕妇，共135名（97％）分娩。 在怀孕的第32周至第38周之间收集了孕妇血液（n  = 139）和尿液（n = 139）。新生儿脐带血（n  = 125）和尿液（n = 125n  = 34）在出生时以及生命的第1、3和6个月期间收集了样本（n  = 132）。高达75％的研究人群的人均收入低于200美元，有19％的人获得了政府资助，而21％的人是单身母亲。至少有20％的人生活在低收入社区。在100％的母亲和新生儿样本中观察到的金属含量超过了检出限，而48％和23.5％的金属显示出可检测的拟除虫菊酯代谢物水平。在大约80％的母血和尿液样本和70％的脐带血样本中检测到全氟烷基酸。在大约30％的新生儿和母亲样本中检测到至少一种有机氯化合物。来自里约热内卢贫困社区的孕妇及其子女暴露于几种有害污染物中。