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Analysis of the Protein-Protein Interaction Network Identifying c-Met as a Target of Gigantol in the Suppression of Lung Cancer Metastasis.
Cancer Genomics & Proteomics ( IF 2.5 ) Pub Date : 2021-4-25 , DOI: 10.21873/cgp.20257
Nithikoon Aksorn 1 , Nattanan Losuwannarak 2 , Sucharat Tungsukruthai 3, 4 , Sittiruk Roytrakul 5 , Pithi Chanvorachote 4, 6
Affiliation  

c-Met (mesenchymal-epithelial transition factor) facilitates cancer progression and is recognized as a promising drug target. The molecular target of gigantol from Dendrobium draconis in suppressing cancer metastasis is largely unknown.

中文翻译:

蛋白质-蛋白质相互作用网络的分析,将 c-Met 鉴定为 Gigantol 抑制肺癌转移的靶点。

c-Met(间充质-上皮转化因子)促进癌症进展,被认为是一个有前途的药物靶点。来自石斛的巨甘醇抑制癌症转移的分子靶点在很大程度上是未知的。
更新日期:2021-04-27
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