ABSTRACT

Introduction: The development of several ROS1 inhibitors means that the importance of accurately identifying ROS1-positive lung cancer patients has never been greater. Therefore, it is crucial that ROS1 testing assays become more standardized.

Areas covered: Based on primary literature, combined with personal diagnostic and research experience, this review provide a pragmatic update on the use of the recently released VENTANA ROS1 (SP384) Rabbit Monoclonal Primary Antibody.

Expert opinion: This assay provides high sensitivity, so it is an excellent analytical option when screening for ROS1 fusions in patients with advanced non-small cell lung carcinomas.

摘要

简介： 几种 ROS1 抑制剂的开发意味着准确识别ROS1阳性肺癌患者的重要性从未如此重要。因此，至关重要的是ROS1测试分析变得更加标准化。

涵盖的领域：基于原始文献，结合个人诊断和研究经验，这篇综述提供了最近发布的 VENTANA ROS1 (SP384) 兔单克隆一抗的实用更新。

专家意见：该检测方法灵敏度高，因此在筛查晚期非小细胞肺癌患者的ROS1融合时是一个极好的分析选择。