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Assessment of some factors of cellular and humoral immunity in radiology workers
Radiation and Environmental Biophysics ( IF 1.7 ) Pub Date : 2021-04-25 , DOI: 10.1007/s00411-021-00911-z
Saadat Ebrahimiyan 1 , Alireza Montazerabadi 2 , Hamed Masoumi 1 , Mohammad Keshtkar 1
Affiliation  

Radiation workers in medical diagnostic departments are occupationally exposed to long-term low-dose ionizing radiation, which may cause radiation-induced side effects. This study investigated subtypes of peripheral blood lymphocytes and immunoglobulin levels in workers who were occupationally exposed to X-ray radiation at the Department of Radiology. Seventeen radiology workers received low levels of ionizing radiation as the study group and 18 individuals who were not exposed to radiation were included as the control group. The percentage of lymphocyte subtypes (CD4+, CD8+ and CD4+/CD8+) and serum levels of immunoglobulins (IgA, IgG and IgM) were measured using peripheral blood samples. Considering all lymphocyte subtypes and serum levels of IgA, IgG and IgM, there was no significant difference between the study and control groups (P > 0.05). There were no significant differences in all mentioned parameters regarding gender (P > 0.05). For the length of employment period, there was a significant difference concerning CD4+/CD8+ (P < 0.05). The findings showed that exposure to low levels of ionizing radiation does not affect the immune system of workers in diagnostic radiology dose level. Because of relatively small samples of workers, it is suggested that these factors be investigated on larger samples of radiology workers.



中文翻译:

放射科工作者细胞和体液免疫若干因素的评价

医疗诊断部门的放射工作人员职业暴露于长期低剂量电离辐射,可能会产生辐射诱发的副作用。本研究调查了放射科职业暴露于 X 射线辐射的工人的外周血淋巴细胞亚型和免疫球蛋白水平。17 名放射科工作人员接受了低水平的电离辐射作为研究组,18 名未接触辐射的人作为对照组。淋巴细胞亚型(CD4 +、CD8 +和 CD4 + /CD8 +) 和免疫球蛋白 (IgA、IgG 和 IgM) 的血清水平是使用外周血样本测量的。综合各淋巴细胞亚型及血清IgA、IgG、IgM水平,研究组与对照组比较差异无统计学意义(P  > 0.05)。所有提及的性别参数均无显着差异(P  > 0.05)。就雇佣期限而言,CD4 + /CD8 + ( P < 0.05)。研究结果表明,暴露于低水平的电离辐射不会影响诊断放射剂量水平的工人的免疫系统。由于工人样本相对较小,建议对较大的放射科工人样本进行调查。

更新日期:2021-04-26
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