The review aims to draw attention to the latest advances in the organoboron chemistry and therapeutic use of organoboron compounds. The synthetic strategies towards boron-containing compounds with proven in vitro and/or in vivo biological activities, including derivatives of boronic acids, benzoxaboroles, benzoxaborines and benzodiazaborines, are summarized. Approaches to the synthesis of hybrid structures containing an organoboron moiety as one of the pharmacophores are considered, and the effect of this modification on the pharmacological activity of the initial molecules is analyzed. On the basis of analysis of the published data, the most promising areas of research in the field of organoboron compounds are identified, including the latest methods of synthesis, modification and design of effective therapeutic agents.

The bibliography includes 246 references.

该综述旨在引起人们对有机硼化学和有机硼化合物治疗用途的最新进展的关注。体外和/或体内证实的含硼化合物的合成策略生物活性，包括硼酸衍生物、苯并恶硼烷、苯并恶硼烷和苯并二氮杂硼烷，进行了总结。考虑了合成含有有机硼部分作为药效团之一的杂化结构的方法，并分析了这种修饰对初始分子药理活性的影响。在对已发表数据的分析的基础上，确定了有机硼化合物领域最有前途的研究领域，包括合成、修饰和设计有效治疗剂的最新方法。

参考书目包括 246 篇参考文献。