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Prevalence and characteristics of persistent symptoms after non-severe COVID-19: a prospective cohort study
European Journal of Clinical Microbiology & Infectious Diseases ( IF 4.5 ) Pub Date : 2021-04-23 , DOI: 10.1007/s10096-021-04261-y
Lucas Armange 1 , François Bénézit 1 , Léa Picard 1 , Charlotte Pronier 2 , Stéphanie Guillot 3 , Pierre-Axel Lentz 4 , François Carré 5 , Pierre Tattevin 1 , Matthieu Revest 1
Affiliation  

We performed a prospective cohort study of 311 outpatients with non-severe COVID-19 (187 women, median age 39 years). Of the 214 (68.8%) who completed the 6-week follow-up questionnaire, 115 (53.7%) had recovered. Others mostly reported dyspnea (n = 86, 40.2%), weight loss (n = 83, 38.8%), sleep disorders (n = 68, 31.8%), and anxiety (n = 56, 26.2%). Of those who developed ageusia and anosmia, these symptoms were still present at week 6 in, respectively, 11/111 (9.9%) and 19/114 (16.7%). Chest CT scan and lung function tests found no explanation in the most disabled patients (n = 23). This study confirms the high prevalence of persistent symptoms after non-severe COVID-19.



中文翻译:

非严重 COVID-19 后持续症状的患病率和特征:一项前瞻性队列研究

我们对 311 名非重症 COVID-19 门诊患者(187 名女性,中位年龄 39 岁)进行了一项前瞻性队列研究。在完成 6 周随访问卷的 214 人(68.8%)中,115 人(53.7%)已经康复。其他人主要报告呼吸困难(n = 86, 40.2%)、体重减轻(n = 83, 38.8%)、睡眠障碍(n = 68, 31.8%)和焦虑(n = 56, 26.2%)。在出现听力障碍和嗅觉丧失的患者中,这些症状在第 6 周仍然存在,分别为 11/111 (9.9%) 和 19/114 (16.7%)。胸部 CT 扫描和肺功能测试在大多数残疾患者中没有发现任何解释(n = 23)。这项研究证实了非严重 COVID-19 后持续症状的高患病率。

更新日期:2021-04-24
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