Abstract

Phytochemical investigation on the 90% EtOH extract of the seeds of Cipadessa cinerascensa led to the isolation of three new limonoids, cinerascenoids A-C (1-3). Structural elucidation of all the compounds were performed by spectral methods such as 1 D and 2 D (¹H-¹H COSY, HMQC, and HMBC) NMR spectroscopy. All the limonoids were in vitro evaluated for their antimicrobial activities against six pathogenic microorganisms. Limonoids 1 and 2 exhibited some activities against three Gram negative bacteria with MIC values less than 60 μg/ml.

中文翻译：

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来自 Cipadessa cinerascensa 种子的抗菌柠檬苦素

摘要

对Cipadessa cinerascensa种子的 90% EtOH 提取物的植物化学研究导致分离出三种新的柠檬苦素类化合物 cinerascenoids AC ( 1-3 )。所有化合物的结构解析均通过光谱方法进行，例如 1 D 和 2 D ( ¹ H - ¹ H COSY、HMQC 和 HMBC) NMR 光谱。所有柠檬苦素类化合物都在体外评估了它们对六种病原微生物的抗菌活性。柠檬苦素1和2对 MIC 值小于 60 μg/ml 的三种革兰氏阴性菌表现出一定的活性。