Background Structural brain lesions are the most common cause of adult-onset epilepsy. The lesion location may contribute to the risk for epileptogenesis, but whether specific lesion locations are associated with a risk for secondary seizure generalization from focal to bilateral tonic-clonic seizures, is unknown.

中文翻译：

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与继发性发作泛化相关的脑损伤位置

背景结构性脑损伤是成人癫痫的最常见原因。病灶位置可能会增加癫痫发生的风险，但具体病灶位置是否与继发性发作从局灶性发作到双侧强直阵挛发作的风险相关尚不清楚。