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Epidemiology, virology and clinical aspects of hantavirus infections: an overview
International Journal of Environmental Health Research ( IF 3.2 ) Pub Date : 2021-04-22 , DOI: 10.1080/09603123.2021.1917527
Sima Singh 1 , Arshid Numan 2 , Dinesh Sharma 3 , Rahul Shukla 4 , Amit Alexander 5 , Gaurav Kumar Jain 6 , Farhan Jalees Ahmad 7 , Prashant Kesharwani 7
Affiliation  

ABSTRACT

At the end of 2019 and 2020s, a wave of coronavirus disease 19 (COVID-19) epidemics worldwide has catalyzed a new era of ‘communicable infectious diseases’. However, the world is not currently prepared to deal with the growing burden of COVID-19, with the unexpected arrival of Hantavirus infection heading to the next several healthcare emergencies in public. Hantavirus is a significant class of zoonotic pathogens of negative-sense single-stranded ribonucleic acid (RNA). Hemorrhagic renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) are the two major clinical manifestations. Till date, there is no effective treatments or vaccines available, public awareness and precautionary measures can help to reduce the spread of hantavirus disease. In this study, we outline the epidemiology, virology, clinical aspects, and existing HFRS and HCPS management approaches. This review will give an understanding of virus-host interactions and will help for the early preparation and effective handling of further outbreaks in an ever-changing environment.



中文翻译:

汉坦病毒感染的流行病学、病毒学和临床方面:概述

摘要

在 2019 年和 2020 年代末,全球范围内的一波冠状病毒病 19 (COVID-19) 流行病催生了“传染性疾病”的新时代。然而,世界目前还没有准备好应对 COVID-19 日益严重的负担,汉坦病毒感染的意外到来将导致接下来的几次公共医疗紧急情况。汉坦病毒是一类重要的负链单链核糖核酸(RNA)人畜共患病原体。出血性肾综合征(HFRS)和汉坦病毒心肺综合征(HCPS)是两种主要的临床表现。迄今为止,尚无有效的治疗方法或疫苗可用,公众意识和预防措施有助于减少汉坦病毒病的传播。在这项研究中,我们概述了流行病学、病毒学、临床方面,以及现有的 HFRS 和 HCPS 管理方法。这篇综述将有助于了解病毒与宿主的相互作用,并有助于在不断变化的环境中及早准备和有效处理进一步的爆发。

更新日期:2021-04-22
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