Background:

Knowledge of the factors that predispose to postdural puncture headache in children may help reduce the occurrence of this complication.

Materials and Methods:

A retrospective cohort study of children who presented to the study institution between 2010 and 2018 was conducted. Children were divided into 2 groups: those who experienced postdural puncture headache and those who did not. The 2 groups were compared with respect to certain demographic, technical, and personnel-related factors. Only children who had opening pressure documented during the procedure were included in the core study group.

Results:

In univariate analysis, children aged ≥10 years, female gender, children with higher body mass index, standard blinded lumbar puncture procedure, use of sedation, higher opening pressure, and presence of pseudotumor cerebri increased the probability of postdural puncture headache. In multivariable logistic regression analysis, presence of pseudotumor cerebri was the only factor that attained statistical significance when the opening pressure was measured and documented.

Conclusions:

The risk factors for postdural puncture headache in a pediatric cohort varied from risk factors that are classically implicated in adults.

中文翻译：

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诱发儿童硬脑膜穿刺后头痛的因素

背景：

了解儿童硬膜穿刺后头痛的易感因素可能有助于减少这种并发症的发生。

材料和方法：

对 2010 年至 2018 年间在研究机构就诊的儿童进行了一项回顾性队列研究。将儿童分为 2 组：有硬膜穿刺后头痛的组和没有出现硬膜穿刺后头痛的组。两组在某些人口统计、技术和人员相关因素方面进行了比较。只有在手术过程中记录了开放压力的儿童才被纳入核心研究组。

结果：

在单变量分析中，年龄≥10岁的儿童、女性、体重指数较高的儿童、标准的盲法腰椎穿刺程序、使用镇静剂、较高的开口压力和假性大脑假瘤的存在增加了硬膜穿刺后头痛的可能性。在多变量逻辑回归分析中，假性脑瘤的存在是在测量和记录开放压力时获得统计学意义的唯一因素。

结论：

儿科队列中硬膜穿刺后头痛的危险因素与成人经典相关的危险因素不同。