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Virulence assessment of enterohepatic Helicobacter species carried by dogs using the wax moth larvae Galleria mellonella as infection model
Helicobacter ( IF 4.4 ) Pub Date : 2021-04-21 , DOI: 10.1111/hel.12808
Sofía Ochoa 1, 2 , Fabiola Fernández 3 , Luis Devotto 4 , Andrés France Iglesias 4 , Luis Collado 1, 2
Affiliation  

Enterohepatic species of the genus Helicobacter (EHH) are emerging pathogens that have been associated with gastrointestinal and hepatobiliary diseases in humans. However, studies on their pathogenicity are scarce. Galleria mellonella is a recently proposed model for the study of virulence in different pathogens, such as Campylobacter spp. and Helicobacter pylori. Despite this, its usefulness in EHH has not yet been evaluated. Therefore, we determined the pathogenic potential of different EHH species isolated from dogs in this infection model.

中文翻译:

以蜡螟幼虫Galleria mellonella为感染模型对犬携带的肠肝螺杆菌的毒力评估

幽门螺杆菌(EHH)属的肠肝菌种是新出现的病原体,与人类的胃肠道和肝胆疾病有关。然而,对其致病性的研究很少。Galleria mellonella是最近提出的用于研究不同病原体(如弯曲杆菌)毒力的模型。和幽门螺杆菌。尽管如此,尚未评估其在 EHH 中的有用性。因此,我们确定了在该感染模型中从狗身上分离的不同 EHH 物种的致病潜力。
更新日期:2021-04-21
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